Nature Communications (Jun 2017)

Ruthenium(II)-catalysed remote C–H alkylations as a versatile platform to meta-decorated arenes

  • Jie Li,
  • Korkit Korvorapun,
  • Suman De Sarkar,
  • Torben Rogge,
  • David J. Burns,
  • Svenja Warratz,
  • Lutz Ackermann

DOI
https://doi.org/10.1038/ncomms15430
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 8

Abstract

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Whileortho-selective C-H activation is well explored, general meta-selective methods are rare and often require directing groups that are retained in the final products. Here the authors show that transient imine groups can be used to direct the meta-functionalization of a range of arenes.