Communications Biology (Dec 2020)
The kinetics of humoral response and its relationship with the disease severity in COVID-19
- Lili Ren,
- Lulu Zhang,
- De Chang,
- Junwen Wang,
- Yongfeng Hu,
- Hong Chen,
- Li Guo,
- Chao Wu,
- Conghui Wang,
- Yingying Wang,
- Ying Wang,
- Geng Wang,
- Siyuan Yang,
- Charles S. Dela Cruz,
- Lokesh Sharma,
- Linghang Wang,
- Dingyu Zhang,
- Jianwei Wang
Affiliations
- Lili Ren
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Lulu Zhang
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- De Chang
- Third Medical Center of Chinese PLA General Hospital
- Junwen Wang
- Wuhan 4th hospital
- Yongfeng Hu
- NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Hong Chen
- The Second Affiliated Hospital of Harbin Medical University
- Li Guo
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Chao Wu
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Conghui Wang
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Yingying Wang
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Ying Wang
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Geng Wang
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- Siyuan Yang
- Laboratory of Infectious Diseases Center of Beijing Ditan Hospital, Capital Medical University
- Charles S. Dela Cruz
- Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine
- Lokesh Sharma
- Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine
- Linghang Wang
- Emergency Department of Infectious Diseases of Beijing Ditan Hospital, Capital Medical University
- Dingyu Zhang
- Research Center for Translational Medicine, Wuhan Jin Yin-tan Hospital
- Jianwei Wang
- NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College
- DOI
- https://doi.org/10.1038/s42003-020-01526-8
- Journal volume & issue
-
Vol. 3,
no. 1
pp. 1 – 7
Abstract
Lili Ren et al. investigate antibody response from 176 COVID-19 patients who presented different stages of their disease. This study suggests the late onset of antibody response as a risk factor for disease severity and a limited role of antibody titers in predicting the disease severity of COVID-19.
