Cells
(Aug 2019)
WNT Signaling in Disease
Li Fang Ng,
Prameet Kaur,
Nawat Bunnag,
Jahnavi Suresh,
Isabelle Chiao Han Sung,
Qian Hui Tan,
Jan Gruber,
Nicholas S. Tolwinski
Affiliations
Li Fang Ng
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Prameet Kaur
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Nawat Bunnag
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Jahnavi Suresh
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Isabelle Chiao Han Sung
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Qian Hui Tan
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Jan Gruber
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
Nicholas S. Tolwinski
Division of Science, Yale-NUS College, Yale-NUS College Research Labs @ E6, E6, 5 Engineering Drive 1, #04-02, Singapore 117608, Singapore
DOI
https://doi.org/10.3390/cells8080826
Journal volume & issue
Vol. 8,
no. 8
Abstract
Read online
Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments.
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