Urate-lowering drugs in the treatment of gout: The unknown about the known

Abstract

The main direction of drug therapy for gout and other diseases associated with hyperuricemia is the long-term use of drugs aimed at correcting the level of uric acid. However, in addition to the urate-lowering effect, these drugs may have other beneficial pleiotropic effects. The article will discuss the additional effects of xanthine oxidase inhibitors, as well as drugs used to treat gout-related diseases that have urate-lowering effects.

Keywords

• gout
• fibrates
• thiazolidinediones
• pioglitazone
• losartan
• arhalofenate
• allopurinol
• febuxostat
• benzbroma-rone