Acute Lung Injury in aortic dissection : new insights in anesthetic management strategies

Abstract

Abstract Acute aortic dissection (AAD) is a severe cardiovascular disease characterized by rapid progress and a high mortality rate. The incidence of acute aortic dissection is approximately 5 to 30 per 1 million people worldwide. In clinical practice, about 35% of AAD patients are complicated with acute lung injury (ALI). AAD complicated with ALI can seriously affect patients’ prognosis and even increase mortality. However, the pathogenesis of AAD combined with ALI remains largely unknown. Given the public health burden of AAD combined with ALI, we reviewed the anesthetic management advances and highlighted potential areas for clinical practice.

Keywords

• Acute aortic dissection
• Acute lung injury
• Ventilation
• Inflammation
• Non-coding RNA
• Anesthetic management