Porphyrin-modified DNA as Construction Material in Supramolecular Chemistry and Nano-architectonics

Abstract

An overview is given on the developments of using porphyrin-modified DNA for the construction of functional assemblies. Strategies for the synthesis and characterisation are presented alongside selected applications where the porphyrin modification has proven to be particularly useful, but also revealed its limitations. We also discuss implications on property and behaviour of the porphyrin-DNA, where similar issues could arise using other hydrophobic and bulky substituents on DNA.

Keywords

• Dna
• Molecular glue
• Nano-architectonics
• Porphyrin
• Supramolecular assembly