Nature Communications (Dec 2022)

Impact of international travel and diarrhea on gut microbiome and resistome dynamics

  • Manish Boolchandani,
  • Kevin S. Blake,
  • Drake H. Tilley,
  • Miguel M. Cabada,
  • Drew J. Schwartz,
  • Sanket Patel,
  • Maria Luisa Morales,
  • Rina Meza,
  • Giselle Soto,
  • Sandra D. Isidean,
  • Chad K. Porter,
  • Mark P. Simons,
  • Gautam Dantas

DOI
https://doi.org/10.1038/s41467-022-34862-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 19

Abstract

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Here, the authors characterize the microbiome and resistome in a longitudinal cohort of 159 international students visiting the Andean city of Cusco, Peru. They find that international travel associates with spread of antimicrobial resistance, and that travelers’ diarrhea increases a persons’ risk for acquiring antimicrobial-resistant pathogens, while a diverse, “healthy” microbiome can be protective against diarrhea.