Frontiers in Cardiovascular Medicine (Jan 2025)
Prognostic implication of right ventricular-pulmonary artery coupling in valvular heart disease
- Zhenni Wu,
- Zhenni Wu,
- Zhenni Wu,
- Mingxing Xie,
- Mingxing Xie,
- Mingxing Xie,
- Li Zhang,
- Li Zhang,
- Li Zhang,
- Qing He,
- Qing He,
- Qing He,
- Lang Gao,
- Lang Gao,
- Lang Gao,
- Mengmeng Ji,
- Mengmeng Ji,
- Mengmeng Ji,
- Yixia Lin,
- Yixia Lin,
- Yixia Lin,
- Yuman Li,
- Yuman Li,
- Yuman Li
Affiliations
- Zhenni Wu
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Zhenni Wu
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Zhenni Wu
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- Mingxing Xie
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Mingxing Xie
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Mingxing Xie
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- Li Zhang
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Li Zhang
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Li Zhang
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- Qing He
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Qing He
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Qing He
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- Lang Gao
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Lang Gao
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Lang Gao
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- Mengmeng Ji
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Mengmeng Ji
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Mengmeng Ji
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- Yixia Lin
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Yixia Lin
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Yixia Lin
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- Yuman Li
- Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- Yuman Li
- Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China
- Yuman Li
- Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China
- DOI
- https://doi.org/10.3389/fcvm.2024.1504063
- Journal volume & issue
-
Vol. 11
Abstract
Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RV–PA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload. If the right ventricle cannot adapt to the elevated afterload by increasing its contractile function, RV-PA uncoupling occurs. RV-PA uncoupling has been shown to be associated with poor outcomes in VHD. This review summarizes the prognostic significance of RV-PA coupling in patients with VHD.
Keywords
- right ventricular-pulmonary artery coupling
- valvular heart disease
- pulmonary hypertension
- congenital heart defect
- right ventricular function
- clinical utility
