Cross Sectional Study of Burn Infections and Antibiotic Susceptibility Pattern for the Improvement of Treatment Policy

Abstract

Introduction: Burn is a devastating form of trauma, and based on its condition, it could run the risk of infections. Infection of wound is a major cause of morbidity and mortality in burn cases. The current study investigates the prevalence of infectious agent in three years and antibiotic resistant pattern to improve and predispose a good policy of treatment in our environment. Materials and Methods: In the present study, a total number of 3330 samples from 713 patients were evaluated for detection of the most prevalent infections and for finding out the antibiotic susceptibility pattern with routine microbiology procedures. Results: Based on the results, 598 samples were reported positive. According to the results Pseudomonas aeruginosa, Coagulase Negative Staphylococcus and Acinetobacter sp. were the three most prevalent bacteria with a prevalence rate of 42.1%, 22.1% and 18.4% respectively. Furthermore, based on the results of distribution and diversity of bacterial infections, wound samples were the most infected samples with 73.6% of total infections. Finally, during these three years, there were no significant changes in the resistance pattern of Gram positive and Gram negative infectious agents. Conclusion: By evaluating the infectious agents during the period of the study, it was found that due to the focus on treatment of Gram negative bacteria, Gram positive bacteria especially Staphylococcus aureus and Coagulase Negative Staphylococcus have at least doubled. This increase in two important nosocomial infections is a next threat of infection and septicemia for burn victims.

Keywords

• Antibiotic resistant
• Burn
• Nosocomial infection
• Treatment policy