Lymphoepithelial Carcinoma in the Lateral Tongue: The Case Report
Sawako Ono,
Hidenori Marunaka,
Hiroyuki Yanai,
Hotaka Kawai,
Kiyofumi Takabatake,
Kenji Nishida,
Tomohiro Toji,
Keisuke Nakano,
Hitoshi Nagatsuka,
Tadashi Yoshino
Affiliations
Sawako Ono
Department of Pathology, Kagawa Prefectural Central Hospital, Takamatsu 760-8557, Japan
Hidenori Marunaka
Department of Otolaryngology Head and Neck Surgery, Okayama University Hospital, Okayama 700-0914, Japan
Hiroyuki Yanai
Department of Pathology, Okayama University Hospital, Okayama 700-0914, Japan
Hotaka Kawai
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-0914, Japan
Kiyofumi Takabatake
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-0914, Japan
Kenji Nishida
Department of Pathology, Okayama University Hospital, Okayama 700-0914, Japan
Tomohiro Toji
Department of Pathology, Okayama University Hospital, Okayama 700-0914, Japan
Keisuke Nakano
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-0914, Japan
Hitoshi Nagatsuka
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-0914, Japan
Tadashi Yoshino
Department of Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-0914, Japan
Lymphoepithelial carcinoma (LEC) of the tongue is a rare subtype of squamous cell carcinoma. Histologically, it is an undifferentiated carcinoma with rich lymphocyte and plasma cell infiltration. The most common location for LEC in the head and neck is the salivary glands, and LEC of the oral cavity is extremely rare. The second case report of LEC in the lateral tongue is presented. In addition, a review of the literature was performed, and the relationship between LEC and Epstein–Barr virus infection was considered.
