Frontiers in Neuroscience (Jan 2018)
Evolving Applications, Technological Challenges and Future Opportunities in Neuromodulation: Proceedings of the Fifth Annual Deep Brain Stimulation Think Tank
- Adolfo Ramirez-Zamora,
- James J. Giordano,
- Aysegul Gunduz,
- Peter Brown,
- Justin C. Sanchez,
- Kelly D. Foote,
- Leonardo Almeida,
- Philip A. Starr,
- Helen M. Bronte-Stewart,
- Wei Hu,
- Cameron McIntyre,
- Wayne Goodman,
- Wayne Goodman,
- Doe Kumsa,
- Warren M. Grill,
- Harrison C. Walker,
- Harrison C. Walker,
- Matthew D. Johnson,
- Jerrold L. Vitek,
- David Greene,
- Daniel S. Rizzuto,
- Dong Song,
- Theodore W. Berger,
- Robert E. Hampson,
- Sam A. Deadwyler,
- Leigh R. Hochberg,
- Leigh R. Hochberg,
- Leigh R. Hochberg,
- Nicholas D. Schiff,
- Paul Stypulkowski,
- Greg Worrell,
- Vineet Tiruvadi,
- Helen S. Mayberg,
- Joohi Jimenez-Shahed,
- Pranav Nanda,
- Sameer A. Sheth,
- Robert E. Gross,
- Scott F. Lempka,
- Luming Li,
- Luming Li,
- Luming Li,
- Wissam Deeb,
- Michael S. Okun
Affiliations
- Adolfo Ramirez-Zamora
- Department of Neurology, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- James J. Giordano
- Department of Neurology, Pellegrino Center for Clinical Bioethics, Georgetown University Medical Center, Washington, DC, United States
- Aysegul Gunduz
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Peter Brown
- Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
- Justin C. Sanchez
- Biological Technologies Office, Defense Advanced Research Projects Agency, Arlington, VA, United States
- Kelly D. Foote
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Leonardo Almeida
- Department of Neurology, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Philip A. Starr
- Department of Neurological Surgery, Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, United States
- Helen M. Bronte-Stewart
- Departments of Neurology and Neurological Sciences and Neurosurgery, Stanford University, Stanford, CA, United States
- Wei Hu
- Department of Neurology, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Cameron McIntyre
- Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States
- Wayne Goodman
- 0Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States
- Wayne Goodman
- 1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States
- Doe Kumsa
- 2Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, United States Food and Drug Administration, White Oak Federal Research Center, Silver Spring, MD, United States
- Warren M. Grill
- 3Department of Biomedical Engineering, Duke University, Durham, NC, United States
- Harrison C. Walker
- 4Division of Movement Disorders, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, United States
- Harrison C. Walker
- 5Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, United States
- Matthew D. Johnson
- 6Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, United States
- Jerrold L. Vitek
- 7Department of Neurology, University of Minnesota, Minneapolis, MN, United States
- David Greene
- 8NeuroPace, Inc., Mountain View, CA, United States
- Daniel S. Rizzuto
- 9Department of Psychology, University of Pennsylvania, Philadelphia, PA, United States
- Dong Song
- 0Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States
- Theodore W. Berger
- 0Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States
- Robert E. Hampson
- 1Physiology and Pharmacology, Wake Forest University School of Medicine, Wake Forest University, Winston-Salem, NC, United States
- Sam A. Deadwyler
- 1Physiology and Pharmacology, Wake Forest University School of Medicine, Wake Forest University, Winston-Salem, NC, United States
- Leigh R. Hochberg
- 2Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, MA, United States
- Leigh R. Hochberg
- 3Center for Neurorestoration and Neurotechnology, Rehabilitation R and D Service, Veterans Affairs Medical Center, Providence, RI, United States
- Leigh R. Hochberg
- 4School of Engineering and Brown Institute for Brain Science, Brown University, Providence, RI, United States
- Nicholas D. Schiff
- 5Laboratory of Cognitive Neuromodulation, Feil Family Brain Mind Research Institute, Weill Cornell Medicine, New York, NY, United States
- Paul Stypulkowski
- 6Medtronic Neuromodulation, Minneapolis, MN, United States
- Greg Worrell
- 7Department of Neurology, Mayo Clinic, Rochester, MN, United States
- Vineet Tiruvadi
- 8Department of Biomedical Engineering, Georgia Institute of Technology, Emory University School of Medicine, Emory University, Atlanta, GA, United States
- Helen S. Mayberg
- 9Departments of Psychiatry, Neurology, and Radiology, Emory University School of Medicine, Emory University, Atlanta, GA, United States
- Joohi Jimenez-Shahed
- 0Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, United States
- Pranav Nanda
- 1Department of Neurological Surgery, The Neurological Institute, Columbia University Herbert and Florence Irving Medical Center, Colombia University, New York, NY, United States
- Sameer A. Sheth
- 1Department of Neurological Surgery, The Neurological Institute, Columbia University Herbert and Florence Irving Medical Center, Colombia University, New York, NY, United States
- Robert E. Gross
- 2Department of Neurosurgery, Emory University, Atlanta, GA, United States
- Scott F. Lempka
- 3Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States
- Luming Li
- 4National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China
- Luming Li
- 5Precision Medicine and Healthcare Research Center, Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Beijing, China
- Luming Li
- 6Center of Epilepsy, Beijing Institute for Brain Disorders, Beijing, China
- Wissam Deeb
- Department of Neurology, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Michael S. Okun
- Department of Neurology, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- DOI
- https://doi.org/10.3389/fnins.2017.00734
- Journal volume & issue
-
Vol. 11
Abstract
The annual Deep Brain Stimulation (DBS) Think Tank provides a focal opportunity for a multidisciplinary ensemble of experts in the field of neuromodulation to discuss advancements and forthcoming opportunities and challenges in the field. The proceedings of the fifth Think Tank summarize progress in neuromodulation neurotechnology and techniques for the treatment of a range of neuropsychiatric conditions including Parkinson's disease, dystonia, essential tremor, Tourette syndrome, obsessive compulsive disorder, epilepsy and cognitive, and motor disorders. Each section of this overview of the meeting provides insight to the critical elements of discussion, current challenges, and identified future directions of scientific and technological development and application. The report addresses key issues in developing, and emphasizes major innovations that have occurred during the past year. Specifically, this year's meeting focused on technical developments in DBS, design considerations for DBS electrodes, improved sensors, neuronal signal processing, advancements in development and uses of responsive DBS (closed-loop systems), updates on National Institutes of Health and DARPA DBS programs of the BRAIN initiative, and neuroethical and policy issues arising in and from DBS research and applications in practice.
Keywords
- deep brain stimulation
- neuromodulation
- epilepsy
- Parkinson's disease
- tremor
- obsessive compulsive disorder
