Regenerative Peripheral Nerve Interface Surgery: Anatomic and Technical Guide

Garrison A. Leach, MD; Riley A. Dean, MD; Nishant Ganesh Kumar, MD; Catherine Tsai, MD; Frank E. Chiarappa, MD; Paul S. Cederna, MD; Theodore A. Kung, MD; Chris M. Reid, MD

doi:10.1097/GOX.0000000000005127

Plastic and Reconstructive Surgery, Global Open (Jul 2023)

Regenerative Peripheral Nerve Interface Surgery: Anatomic and Technical Guide

Garrison A. Leach, MD,
Riley A. Dean, MD,
Nishant Ganesh Kumar, MD,
Catherine Tsai, MD,
Frank E. Chiarappa, MD,
Paul S. Cederna, MD,
Theodore A. Kung, MD,
Chris M. Reid, MD

Affiliations

Garrison A. Leach, MD: From the * Department of General Surgery, Division of Plastic Surgery, University of California San Diego, La Jolla, Calif.
Riley A. Dean, MD: From the * Department of General Surgery, Division of Plastic Surgery, University of California San Diego, La Jolla, Calif.
Nishant Ganesh Kumar, MD: † Section of Plastic and Reconstructive Surgery and the Department of Biomedical Engineering, University of Michigan, Ann Arbor, Mich.
Catherine Tsai, MD: From the * Department of General Surgery, Division of Plastic Surgery, University of California San Diego, La Jolla, Calif.
Frank E. Chiarappa, MD: ‡ Department of Orthopedic Surgery, University of California San Diego, La Jolla, Calif.
Paul S. Cederna, MD: † Section of Plastic and Reconstructive Surgery and the Department of Biomedical Engineering, University of Michigan, Ann Arbor, Mich.
Theodore A. Kung, MD: † Section of Plastic and Reconstructive Surgery and the Department of Biomedical Engineering, University of Michigan, Ann Arbor, Mich.
Chris M. Reid, MD: From the * Department of General Surgery, Division of Plastic Surgery, University of California San Diego, La Jolla, Calif.

DOI: https://doi.org/10.1097/GOX.0000000000005127
Journal volume & issue: Vol. 11, no. 7
p. e5127

Abstract

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Summary:. Regenerative peripheral nerve interface (RPNI) surgery has been demonstrated to be an effective tool as an interface for neuroprosthetics. Additionally, it has been shown to be a reproducible and reliable strategy for the active treatment and for prevention of neuromas. The purpose of this article is to provide a comprehensive review of RPNI surgery to demonstrate its simplicity and empower reconstructive surgeons to add this to their armamentarium. This article discusses the basic science of neuroma formation and prevention, as well as the theory of RPNI. An anatomic review and discussion of surgical technique for each level of amputation and considerations for other etiologies of traumatic neuromas are included. Lastly, the authors discuss the future of RPNI surgery and compare this with other active techniques for the treatment of neuromas.

Published in Plastic and Reconstructive Surgery, Global Open

ISSN: 2169-7574 (Online)
Publisher: Wolters Kluwer
Country of publisher: United States
LCC subjects: Medicine: Surgery
Website: http://www.prsgo.com

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