The viscosity and thrombocytic-aggregation disorders in patients, suffering myocardial infarction with the ST segment elevation

Abstract

Objective. Analysis of changes in viscosity and disorders of the thrombocytes-aggregation process under impact of various tactical, diagnostic and intervention approaches in patients, suffering myocardial infarction with persistent elevation of ST segment in presence of multivascular affection of coronary arteries. Materials and methods. In the investigation four tactical and treatment-diagnostic approaches were used through year of observation. Results. In patients, suffering myocardial infarction and persistent elevation of ST segment the hyperviscosity and hypercoagulation syndromes were revealed, which have manifested in first weeks by compensatory growth of thrombocytes quantity, the blood viscosity, level of fibrinogen and aggregation properties of thrombocytes. Conduction of additional more profound examination of coronary blood circulation and further application of postponed stenting of the infarction-dependent arteries have promoted lesser amplitude of fluctuations of all laboratory indices, than in other tactical and treatment approaches. Conclusion. Standard tactical and treatment-diagnostic principles in management of such category of patients do not permit to improve the state of the viscosity and coagulation-aggregation parameters principally, even while application of double antiaggregation therapy.

Keywords

• treatment-diagnostic approaches; the blood circulation; syndromes of hyperviscosity and hypercoagulation; atheromatous process; thrombocytes.