Zhejiang Daxue xuebao. Lixue ban (Sep 2013)

Copper-catalyzed highly regioselective 2-thiolation of 2, x-dibromopyridines(铜催化的2，x-二溴吡啶与硫酚的高度区域选择性偶联反应)

LÜZe-guang(吕泽光),
ZHOUQi-zhong(周其忠)

Affiliations

LÜZe-guang(吕泽光): 1. Deparment of Chemistry, Taizhou University, Taizhou 318000, Zhejiang Province, China( 1.台州学院化学系，浙江　台州　318000)
ZHOUQi-zhong(周其忠): 1. Deparment of Chemistry, Taizhou University, Taizhou 318000, Zhejiang Province, China( 1.台州学院化学系，浙江　台州　318000)

DOI: https://doi.org/10.3785/j.issn.1008-9497.2013.05.015
Journal volume & issue: Vol. 40, no. 5
pp. 548 – 552

Abstract

以CuI为催化剂，L-脯氨酸为配体，Cs2CO3为碱，DMF为溶剂，在30 ℃下，用2，x-二溴吡啶和硫酚或硫醇反应，高产率和高区域选择性地得到2位烃硫基取代的吡啶.该反应可应用于药物的合成.

Published in Zhejiang Daxue xuebao. Lixue ban

ISSN: 1008-9497 (Print)
Publisher: Zhejiang University Press
Country of publisher: China
LCC subjects: Science: Mathematics: Instruments and machines: Electronic computers. Computer science; Science: Physics
Website: https://www.zjujournals.com/sci/EN/1008-9497/home.shtml

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