Persistent craniopharyngeal canal is a congenital defect between sella turcica and nasopharynx. It is considered to develope from incomplete closure of Rathke's pouch, the precursor of adenohypophysis. Persistent craniopharyngeal canal can be associated pituitary anomalies and other central nervous system anomalies. We presented a case of persistent craniopharyngeal canal with posterior pituitary ectopia.