PLoS ONE (Jan 2024)

Cost-effectiveness and cost-utility analyses of three different gargles in the treatment of chronic periodontitis.

  • Xin Chen,
  • Wenzhi Niu,
  • Guangyu Hu,
  • Changfeng Chen

DOI
https://doi.org/10.1371/journal.pone.0302592
Journal volume & issue
Vol. 19, no. 5
p. e0302592

Abstract

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ObjectiveThis study aimed to investigate the economics of three different gargles in the treatment of chronic periodontitis.MethodsA total of 108 patients with periodontitis received one of the following three gargles: xipayi, compound chlorhexidine, or Kangfuxin gargle. The basic information of the patients, the costs of the gargles, the periodontal indexes before and after treatment, and the scores of the 3-level version of the EuroQol Five Dimensions Questionnaire were collected. The cost-effectiveness and cost-utility of the various gargles were determined.ResultsThe cost-effectiveness ratios (CER) of the three groups after treatment were 1828.75, 1573.34, and 1876.92 RMB, respectively. The utility values before treatment were 0.92, 0.90, and 0.91, respectively, and the utility values after treatment were 0.98, 0.98, and 0.97, respectively. The cost-utility ratios (CURs) were 213.43, 195.61, and 301.53 RMB, respectively.ConclusionsFor each increase in effective rate and quality-adjusted life years, the treatment cost of periodontitis patients was lower than the gross domestic product per capita of Jiangsu Province, indicating that the treatment cost is completely worth it. The CER and CUR results were the same, and the compound chlorhexidine group was the lowest, demonstrating that when the same therapeutic effect was achieved, it cost the least.