A Caenorhabditis elegans Host Model Correlates with Invasive Disease Caused by Staphylococcus aureus Recovered during an Outbreak in Neonatal Intensive Care

Kaiyu Wu; Andrew E Simor; Mary Vearncombe; Jo-Ann McClure; Kunyan Zhang

doi:10.1155/2012/543817

Canadian Journal of Infectious Diseases and Medical Microbiology (Jan 2012)

A Caenorhabditis elegans Host Model Correlates with Invasive Disease Caused by Staphylococcus aureus Recovered during an Outbreak in Neonatal Intensive Care

Kaiyu Wu,
Andrew E Simor,
Mary Vearncombe,
Jo-Ann McClure,
Kunyan Zhang

Affiliations

Kaiyu Wu: Department of Pathology and Laboratory Medicine, University of Calgary, Canada
Andrew E Simor: Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Mary Vearncombe: Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Jo-Ann McClure: Centre for Antimicrobial Resistance, Alberta Health Services/Calgary Laboratory Services/University of Calgary, Calgary, Alberta, Canada
Kunyan Zhang: Department of Pathology and Laboratory Medicine, University of Calgary, Canada

DOI: https://doi.org/10.1155/2012/543817
Journal volume & issue: Vol. 23, no. 3
pp. 130 – 134

Abstract

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BACKGROUND: Caenorhabditis elegans has previously been used as a host model to determine the virulence of clinical methicillin-resistant Staphylococcus aureus isolates. In the present study, methicillin-susceptible S aureus (MSSA) strains associated with an outbreak in a neonatal intensive care unit (NICU) were investigated using the C elegans model.

Published in Canadian Journal of Infectious Diseases and Medical Microbiology

ISSN: 1712-9532 (Print); 1918-1493 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Science: Microbiology
Website: https://onlinelibrary.wiley.com/journal/9575

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