Study on the Etiology, Pathogenesis and Clinical Symptoms of Hashimoto’s Thyroiditis

Abstract

Hashimoto’s thyroiditis (HT) is a common thyroid autoimmune disease with multiple impacts on the thyroid of patients. The main clinical manifestations include disorder of humoral and cellular immunity, and morphological and functional changes in the thyroid. There have been a variety of factors influencing the development of HT, such as genes, environment, uneven nutrition intake, and so on. The pathogenesis is complex and there is no method to completely cure and reverse HT. However, the exact etiology and pathogenesis have not been fully clarified. Therefore, the current research task is to understand the clinical manifestations, explore the pathogenic factors and study the pathogenesis. This article briefly introduces the main clinical features of HT and summarizes the research results of different scholars on the pathogenic factors and pathogenesis.