A Compact Graph Convolutional Network With Adaptive Functional Connectivity for Seizure Prediction

Abstract

Seizure prediction using EEG has significant implications for the daily monitoring and treatment of epilepsy patients. However, the task is challenging due to the underlying spatiotemporal correlations and patient heterogeneity. Traditional methods often use large-scale models with independent components to capture the spatial and temporal features of EEG separately or explore shared patterns among patients with the help of pre-defined functional connectivity. In this paper, we propose a compact model, called the graph convolutional network based on adaptive functional connectivity (AFC-GCN), for seizure prediction. The model can adaptively infer evolution of functional connectivity in epilepsy patients during seizures through data-driven methods and synchronously analyze spatiotemporal response of functional connectivity in multiple topologies. On CHB-MIT datasets, the experimental results demonstrate that AFC-GCN achieves accurate and robust performance with low complexity. (AUC: 0.9820, accuracy: 0.9815, sensitivity: 0.9802, FPR: 0.0172). The proposed method has the potential to predict seizure during daily monitoring.

Keywords

• Electroencephalogram
• graph convolutional network
• adaptive functional connectivity
• seizure prediction