Clinical Ophthalmology (Jun 2023)
Spotlight on Schlemm’s Canal MicroStent Injection in Patients with Glaucoma
Abstract
Isabella V Wagner,1 Bryan Ang,2 Leticia Checo,1 Derya Simsek,3 Christian Draper,1 Syril Dorairaj1 1Department of Ophthalmology, Mayo Clinic, Jacksonville, FL, USA; 2Department of Ophthalmology, Tan Tock Seng Hospital, Singapore; 3Department of Ophthalmology, Baskent University Medical School, Ankara, TurkeyCorrespondence: Syril Dorairaj, Department of Ophthalmology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, USA, Tel +1 904-953-2377, Fax +1 904-953-7040, Email [email protected]: Minimally invasive glaucoma surgery (MIGS) has revolutionized glaucoma care with its favorable safety profile and ability to delay or minimize the need for traditional, bleb-based procedures. Microstent device implantation is a type of angle-based MIGS, which reduces intraocular pressure (IOP) through bypass of the juxtacanalicular trabecular meshwork (TM) and facilitation of aqueous outflow into the Schlemm’s canal. Although there are limited microstent devices on the market, multiple studies have evaluated the safety and efficacy of iStent® (Glaukos Corp.), iStent Inject® (Glaukos Corp.), and Hydrus® Microstent (Alcon) in the treatment of mild-to-moderate open-angle glaucoma, with and without concurrent phacoemulsification. This review attempts to provide a comprehensive evaluation of injectable angle-based microstent MIGS devices in the treatment of glaucoma.Keywords: microstent injection, Schlemm’s canal, Hydrus microstent, iStent, glaucoma, aqueous outflow
