Correlation of Environment, Nutrition, Genetics, Epigenetics, Microbiota with Neonatal Fetus Development

Abstract

Abstract Introduction: From the moment of conception the human being is predisposed to undergo changes in fetal and neonatal development due to various external factors that occur throughout life and can in the long term influence the phenotypic expression of the new being. Objective: The objective of this work is to determine the relationship between the environment, nutrition, genetics, epigenetics and microbiota with neonatal fetus development and how they influence the phenotypic expression of the new being. Methods: A non-systematic search was performed in electronic databases such as COCHRANE, PUBMED, MEDLINE, etc. The bibliographic research was carried out in the period between October 2019 and January 2020. The studies carried out from 2007 to 2019, in the languages of Spanish and English, were included. Results: We found 51 bibliographic sources related to the subject, of which by means of a last simplification, 30 scientific articles were used that provided important information on the subject, and 21 articles were excluded. Conclusion: Research on methods to detect these interactions and to understand the mechanisms of these interactions is just beginning. However, there is evidence that they play an important role in human development.

Keywords

• neonatal development, epigenetics, microbiota, fetal development, nutrition.