mBio
(Apr 2021)
Elucidating the Antiviral Mechanism of Different MARCH Factors
Supawadee Umthong,
Brian Lynch,
Uddhav Timilsina,
Brandon Waxman,
Emily B. Ivey,
Spyridon Stavrou
Affiliations
Supawadee Umthong
Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA
Brian Lynch
Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA
Uddhav Timilsina
Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA
Brandon Waxman
Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA
Emily B. Ivey
Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA
Spyridon Stavrou
ORCiD Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA
DOI
https://doi.org/10.1128/mBio.03264-20
Journal volume & issue
Vol. 12,
no. 2
Abstract
Read online
This study examines the mechanism utilized by different MARCH proteins to restrict retrovirus infection. MARCH proteins block the incorporation of envelope glycoproteins to the budding virions.
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