Microwave Ablation and Immune Activation in the Treatment of Recurrent Colorectal Lung Metastases: A Case Report

Abstract

We present a patient with colorectal metastases confined to the lungs and treated with multiple resections until this was not an option anymore, followed by stereotactic body radiation therapy until this option was drained. Then, the patient was successfully treated with multiple microwave ablations combined with immunological activation targeting the programmed cell death 1 receptor (PD-1), possibly instigating a powerful abscopal effect. Techniques, doses, and radiological findings are presented.

Keywords

• Metastasis
• Microwave
• Navigated ablation
• Cascination
• Resection
• Radiotherapy
• Immune activation
• Pembrolizumab
• Colorectal cancer
• Lung