Revista da Sociedade Brasileira de Medicina Tropical (Nov 2020)

First report of the aac(6’)-Ib-cr gene in Providencia stuartii isolates in Brazil

  • Sivoneide Maria da Silva,
  • Bárbara de Azevedo Ramos,
  • Ana Vitória Araújo Lima,
  • Rafael Artur Cavalcanti Queiroz de Sá,
  • Jailton Lobo da Costa Lima,
  • Maria Amélia Vieira Maciel,
  • Patrícia Maria Guedes Paiva,
  • Márcia Vanusa da Silva,
  • Maria Tereza dos Santos Correia,
  • Maria Betânia Melo de Oliveira

DOI
https://doi.org/10.1590/0037-8682-0524-2019
Journal volume & issue
Vol. 54

Abstract

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Abstract INTRODUCTION: The aac(6’)-Ib-cr and bla KPC genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world. METHODS: These genes were investigated in 28 P. stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by PCR and sequencing. RESULTS: The aac(6’)-Ib-cr gene was detected in 16 resistant isolates, and the bla KPC gene was seen in 14. CONCLUSIONS: The presence of these genes in P. stuartii multi- and extensively drug-resistant isolates indicates that the resistance arsenal of this species is increasing, thus limiting the therapeutic options.

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