Ketorolac in a multimodal pain management scheme

Abstract

Pain, as a powerful trigger of stress response to surgery, largely determines the results of surgical treatment through neurohormonal, endocrine, immune, metabolic and hemostatic mechanisms. The most commonly used NSAID is ketorolac (ketorol) which is administered parenterally. Improvements in the quality of postoperative analgesia predetermined the creation of a protocol with NSAIDs as the basic medications. For the treatment of postoperative pain, the Clinical Centre currently uses a combination of drugs with different mechanisms of action depending on the type of surgery, the nature and severity of primary and associated pathology in patients. For this purpose, NSAIDs are initially administered as they reduce activation of nocicep-tors in peripheral tissues; anesthesia with preferential inhibition of transmission of pain impulse at the segmental and suprasegmental levels is also applied.

Keywords

• нпвп
• кеторолак
• амбулаторная хирургия
• мультимодальная анальгезия
• nsaid
• ketorolac
• outpatient surgery
• multimodal analgesia