Interleukin-4 production in BALB/c mice immunized with Anisakis simplex

Abstract

We investigated the interleukin (IL-4) levels in BALB/c mice immunized with Anisakis extract in single or multiple doses and in mice orally infected with a larva. From animals immunized maximum responses were obtained with the multiple doses with an only IL-4 peak. Conversely, in the mice inoculated with a larva per os, the IL-4 levels showed two peaks of different rates.

Keywords

• interleukin-4
• BALB/c
• Anisakis simplex