Nature Communications (Apr 2018)

Random sequences rapidly evolve into de novo promoters

  • Avihu H. Yona,
  • Eric J. Alm,
  • Jeff Gore

DOI
https://doi.org/10.1038/s41467-018-04026-w
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Bacterial promoters initiate gene transcription and have distinct sequence features. Here, the authors show that random sequences that contain no information are just on the verge of functioning as promoters in Escherichia coli.