Nature Communications (Jul 2022)
Single-cell transcriptome atlas of the human corpus cavernosum
- LiangYu Zhao,
- Sha Han,
- HengChuan Su,
- JianYing Li,
- ErLei Zhi,
- Peng Li,
- ChenCheng Yao,
- RuHui Tian,
- HuiXing Chen,
- HuiRong Chen,
- JiaQiang Luo,
- ChenKun Shi,
- ZhiYong Ji,
- JianLin Hu,
- Gang Wu,
- WeiDong Zhou,
- YuXin Tang,
- YuZhuo Chen,
- GuiTing Lin,
- Tom F. Lue,
- DengLong Wu,
- Zheng Li
Affiliations
- LiangYu Zhao
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Sha Han
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- HengChuan Su
- Department of Urology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University
- JianYing Li
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- ErLei Zhi
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Peng Li
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- ChenCheng Yao
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- RuHui Tian
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- HuiXing Chen
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- HuiRong Chen
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- JiaQiang Luo
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- ChenKun Shi
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- ZhiYong Ji
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- JianLin Hu
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Gang Wu
- Department of Urology, Tongji Hospital, School of Medicine, Tongji University
- WeiDong Zhou
- Department of Urology, Tongji Hospital, School of Medicine, Tongji University
- YuXin Tang
- Department of Urology, Department of Interventional Medicine, Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University
- YuZhuo Chen
- Department of Ultrasound, The Fifth Affiliated Hospital, Sun Yat-sen University
- GuiTing Lin
- Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California
- Tom F. Lue
- Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California
- DengLong Wu
- Department of Urology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University
- Zheng Li
- Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- DOI
- https://doi.org/10.1038/s41467-022-31950-9
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 16
Abstract
The corpus cavernosum is the most important structure for penile erection, and its dysfunction causes physiological and psychological problems. Here the authors perform single-cell RNA-sequencing on corpus cavernosum samples from males with normal erection and erectile dysfunction patients, providing insights into this pathology.
