Morphofunctional parameters of the immune system of chickens after dissemination of bacteria Pseudomonas aeruginosa

Abstract

Infectious diseases caused by ubiquitous bacteria with variability of virulence factors and multiple antibiotic resistance reliably often represent the structure of the general pathology of poultry. The aim of the study was to analyze dynamics of morph functional parameters of immune system of chickens in experimental pseudomonas infection. The initiation, development, and outcome of the experimental infectious process were considered using bacteriological and immunological methods with vital dye. Dissemination ofP. aeruginosabacteria revealed significant increase in extravasation of lung blood vessels, signs of hemodynamic disorders, and development of dystrophic and compensatory-adaptive processes. Pathogenic mechanisms are mediated by the dynamics of changes in reticuloendothelial and lymph epithelial systems: accidental transformation of thymus, atrophy of bursa of Fabricius, hyperplasia of esophageal and cecum lymphoid follicles, Meckels diverticulum, and spleen.

Keywords

• poultry
• immunoglobulins
• antigens
• microorganisms
• differentiation
• thymus transformation
• bursa atrophy
• splenomegaly