AlphaFold and the future of structural biology

Randy J. Read; Edward N. Baker; Charles S. Bond; Elspeth F. Garman; Mark J. van Raaij

doi:10.1107/S2052252523004943

IUCrJ (Jul 2023)

AlphaFold and the future of structural biology

Randy J. Read,
Edward N. Baker,
Charles S. Bond,
Elspeth F. Garman,
Mark J. van Raaij

Affiliations

Randy J. Read: Cambridge Institute for Medical Research, University of Cambridge, The Keith Peters Building, Hills Road, Cambridge CB2 0XY, United Kingdom
Edward N. Baker: School of Biological Sciences, University of Auckland, Auckland, New Zealand
Charles S. Bond: School of Molecular Sciences, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
Elspeth F. Garman: Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford OX1 3QU, United Kingdom
Mark J. van Raaij: Departamento de Estructura de Macromoleculas, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, 28049 Madrid, Spain

DOI: https://doi.org/10.1107/S2052252523004943
Journal volume & issue: Vol. 10, no. 4
pp. 377 – 379

Abstract

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This editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology.

Published in IUCrJ

ISSN: 2052-2525 (Online)
Publisher: International Union of Crystallography
Country of publisher: United Kingdom
LCC subjects: Science: Chemistry: Crystallography
Website: https://journals.iucr.org/m/

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