Comparison of the pregnancy outcomes of the patients with severe symptoms who received medical treatment for COVID-19 versus the patients with mild-moderate symptoms

Abstract

Objective COVID-19 has spread all over the world since December 2019. There is little evidence concerning maternal or perinatal outcomes up to now. The present study aimed to compare pregnant women with severe and mild-moderate COVID-19 symptoms in terms of maternal and perinatal outcomes. Methods The study group was composed of pregnant patients admitted to our tertiary center with symptoms and diagnosed with severe acute respiratory syndrome Coronavirus 2 (SARS-Cov-2). The patients were categorized into two groups: severe and not severe, and women determined as in the severe disease group were hospitalized. The patients were continued to their routine follow-up, their maternal and perinatal outcomes were recorded. Results A total of 52 patients were enrolled in the study: 59.6% presented mild-moderate disease and 40.4% presented severe disease. The gestational age at diagnosis of COVID-19 was higher in the patients with severe symptoms than in patients with mild-moderate symptoms (median 20.5 vs 28.0, respectively, p=0.048). There was no difference between those two groups in terms of maternal and perinatal outcomes. Conclusion Despite the growing number of published studies on COVID-19 in pregnancy, there are insufficient quality data to draw conclusions about the severity of COVID-19 in symptomatic pregnant women and its maternal and neonatal consequences. In our study, there is no difference between mild-moderate and severe groups in terms of maternal and perinatal outcomes.