Imatinib-Induced Tremor in a Patient with Chronic Myeloid Leukemia in Chronic Phase

Abstract

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by three phases: chronic, accelerated, and blast phase. However; first- and second-generation tyrosine kinase inhibitors are used for the treatment of CML with common and uncommon adverse events. Here, we report a 24-year-old male with CML in chronic phase started on imatinib as upfront medication who developed tremor and recovered spontenously after 3 years.

Keywords

• chronic myeloid leukemia
• imatinib
• side effects
• tremor
• tyrosine kinases