Royal Society Open Science (Mar 2021)

Effectiveness and resource requirements of test, trace and isolate strategies for COVID in the UK

  • Bobby He,
  • Sheheryar Zaidi,
  • Bryn Elesedy,
  • Michael Hutchinson,
  • Andrei Paleyes,
  • Guy Harling,
  • Anne M. Johnson,
  • Yee Whye Teh,

DOI
https://doi.org/10.1098/rsos.201491
Journal volume & issue
Vol. 8, no. 3

Abstract

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We use an individual-level transmission and contact simulation model to explore the effectiveness and resource requirements of various test-trace-isolate (TTI) strategies for reducing the spread of SARS-CoV-2 in the UK, in the context of different scenarios with varying levels of stringency of non-pharmaceutical interventions. Based on modelling results, we show that self-isolation of symptomatic individuals and quarantine of their household contacts has a substantial impact on the number of new infections generated by each primary case. We further show that adding contact tracing of non-household contacts of confirmed cases to this broader package of interventions reduces the number of new infections otherwise generated by 5–15%. We also explore impact of key factors, such as tracing application adoption and testing delay, on overall effectiveness of TTI.

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