Metformin reduces PD-L1 on tumor cells and enhances the anti-tumor immune response generated by vaccine immunotherapy

• Luis Enrique Munoz,
• Richa Sharma,
• Ramireddy Bommireddy,
• Lenore Monterroza,
• Rohini N. Guin,
• Sarah G. Samaranayake,
• Christopher D. Pack,
• Sampath Ramachandiran,
• Shaker J.C. Reddy,
• Mala Shanmugam,
• Periasamy Selvaraj

Affiliations

Luis Enrique Munoz

1 Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA

Richa Sharma

2 Hematology and Medical Oncology, Emory University, Atlanta, Georgia, USA

Ramireddy Bommireddy

1 Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA

Lenore Monterroza

1 Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA

Rohini N. Guin

1 Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA

Sarah G. Samaranayake

1 Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA

Christopher D. Pack

3 Metaclipse Therapeutics Corporation, Atlanta, Georgia, USA

Sampath Ramachandiran

3 Metaclipse Therapeutics Corporation, Atlanta, Georgia, USA

Shaker J.C. Reddy

3 Metaclipse Therapeutics Corporation, Atlanta, Georgia, USA

Mala Shanmugam

2 Hematology and Medical Oncology, Emory University, Atlanta, Georgia, USA

Periasamy Selvaraj

1 Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA