Nature Communications (Nov 2017)
Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment
- Yanyun Gu,
- Xiaokai Wang,
- Junhua Li,
- Yifei Zhang,
- Huanzi Zhong,
- Ruixin Liu,
- Dongya Zhang,
- Qiang Feng,
- Xiaoyan Xie,
- Jie Hong,
- Huahui Ren,
- Wei Liu,
- Jing Ma,
- Qing Su,
- Hongmei Zhang,
- Jialin Yang,
- Xiaoling Wang,
- Xinjie Zhao,
- Weiqiong Gu,
- Yufang Bi,
- Yongde Peng,
- Xiaoqiang Xu,
- Huihua Xia,
- Fang Li,
- Xun Xu,
- Huanming Yang,
- Guowang Xu,
- Lise Madsen,
- Karsten Kristiansen,
- Guang Ning,
- Weiqing Wang
Affiliations
- Yanyun Gu
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Xiaokai Wang
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Junhua Li
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Yifei Zhang
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Huanzi Zhong
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Ruixin Liu
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Dongya Zhang
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Qiang Feng
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Xiaoyan Xie
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Jie Hong
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Huahui Ren
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Wei Liu
- Renji Hospital affiliated to Shanghai Jiaotong University Medical School
- Jing Ma
- Renji Hospital affiliated to Shanghai Jiaotong University Medical School
- Qing Su
- Xinhua Hospital affiliated to Shanghai Jiaotong University Medical School
- Hongmei Zhang
- Xinhua Hospital affiliated to Shanghai Jiaotong University Medical School
- Jialin Yang
- MinHang Central Hospital affiliated to Fudan University Medical School
- Xiaoling Wang
- Dalian Institute of Chemical Physics, Chinese Academy of Science
- Xinjie Zhao
- Dalian Institute of Chemical Physics, Chinese Academy of Science
- Weiqiong Gu
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Yufang Bi
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Yongde Peng
- Shanghai General Hospital, Shanghai Jiaotong University
- Xiaoqiang Xu
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Huihua Xia
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Fang Li
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Xun Xu
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Huanming Yang
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Guowang Xu
- Dalian Institute of Chemical Physics, Chinese Academy of Science
- Lise Madsen
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Karsten Kristiansen
- BGI-Shenzhen, China National GeneBank-Shenzhen
- Guang Ning
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- Weiqing Wang
- Shanghai National Research Centre for Endocrine and Metabolic Diseases, State Key Laboratory of Medical Genomics, Shanghai Institute for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
- DOI
- https://doi.org/10.1038/s41467-017-01682-2
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 12
Abstract
The authors examine the effects of antidiabetic medication on the gut microbiome and bile acid composition and show that these data can be used to stratify treatment regimens for type 2 diabetes.
