Nature Communications (Jul 2018)

Unperturbed expression bias of imprinted genes in schizophrenia

  • Attila Gulyás-Kovács,
  • Ifat Keydar,
  • Eva Xia,
  • Menachem Fromer,
  • Gabriel Hoffman,
  • Douglas Ruderfer,
  • Ravi Sachidanandam,
  • Andrew Chess

DOI
https://doi.org/10.1038/s41467-018-04960-9
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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This study analyzes allelic expression bias in post-mortem brains of healthy individuals and those diagnosed with schizophrenia or bipolar disorder. The study shows that the number of imprinted genes is consistent with low estimates, and that allelic bias is independent of psychiatric disease status.