Le virus de la leucémie bovine et l’homéostasie du compartiment lymphocytaire périphérique

Abstract

Bovine leukaemia virus and peripheral blood lymphocytes homeostasis. Bovine leukaemia virus (BLV) is the etiological agent of a lymphoproliferative disease in cattle. This retrovirus can also be transmitted experimentally to the ovine species, in which pathology is more rapid and more frequent. In this model, infection leads to an increased cell turnover. This accelerated lymphocyte dynamics might be related to viral expression which induces cellular proliferation and host cell destruction by the immune system.

Keywords

• BLV
• sheep
• lymphocyte
• homeostasis
• cell dynamics
• immune response