New Allyl Derivative of Curcumin: Synthesis and Crystal Structure of (1<i>E</i>,6<i>E</i>)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione
Anna A. Druzina,
Olga B. Zhidkova,
Sergey A. Anufriev,
Ekaterina V. Dubasova,
Ivan V. Ananyev,
Samya Banerjee,
Igor B. Sivaev,
Vladimir I. Bregadze
Affiliations
Anna A. Druzina
A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, Russia
Olga B. Zhidkova
A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, Russia
Sergey A. Anufriev
A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, Russia
Ekaterina V. Dubasova
N.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky Avenue, 119991 Moscow, Russia
Ivan V. Ananyev
A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, Russia
Samya Banerjee
Department of Chemistry, Indian Institute of Technology (BHU), Varanasi 221005, UP, India
Igor B. Sivaev
A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, Russia
Vladimir I. Bregadze
A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Str., 119991 Moscow, Russia
A new allyl derivative of curcumin containing three allyl groups (1E,6E)-4-allyl-1,7-bis(4′-allyloxy-3′-methoxyphenyl)hepta-1,6-diene-3,5-dione was synthesized by the reaction of curcumin with the excess of allyl bromide in the presence of K2CO3 in acetone under reflux. The triple-allylated curcumin was characterized by 1H and 13C-NMR spectroscopy and single-crystal X-ray diffraction analysis.
