Nature Communications (Jan 2020)
Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
Abstract
Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material chemistry. Here, the authors show a regioselective trifunctionalization of 1,3-enynes proceeding through double C-F bond formation and concomitant installation of a -NSO2Ph group to the allene moiety.