Investigation of the presence of brlA, abaA, and wetA conidiation genes in Dermatophytes

Abstract

Background: Dermatophytes are common causes of cutaneous infections in humans and animals, which mostly reproduce by an asexual process. Such types of reproduction in many filamentous fungi are usually regulated by brlA, abaA, and wetA genes. The presence of these genes in dermatophytes was investigated. Materials & Methods: Conidiation genes represented by brlA, abaA, and wetA were determined in seven strains of dermatophytes using a polymerase chain reaction (PCR) method. Results: All strains of Microsporum canis and one strain of Microsporum ferrugineum (MH383043) were shown to have all three specific conidiation genes, which were absent in other strains, except for Trichophyton interdigitale which had only the abaA gene. Conclusion: Dermatophytes content of brlA, abaA, and wetA genes is variable and strain-dependent. The conidiation process in most dermatophytes is assumed to be under the control of other genes not included in this study.

Keywords

• dermatophytes
• brla
• abaa
• weta
• conidiation