Chain-End Effect for Intermediate Water Formation of Poly(2-Methoxyethyl Acrylate)

Abstract

Abstract Intermediate water (IW), which is formed not only by biocompatible polymers such as poly(2-methoxyethyl acrylate) (PMEA), but also by biomacromolecules, plays a key role in determining the biocompatibility of synthetic polymers. In this study, we compare the well-defined linear and cyclic PMEA using differential scanning calorimetry and atomic force microscopy. This study aims to clarify the role of the chain-end effect in IW formation to establish design guidelines for biomaterials.

Keywords

• intermediate water
• hydration state
• chain-end effect
• poly(2-methoxyethyl acrylate)
• cyclic polymers
• interfacial structures