Journal of Epidemiology (Mar 2019)

The Circulatory Risk in Communities Study (CIRCS): A Long-Term Epidemiological Study for Lifestyle-Related Disease Among Japanese Men and Women Living in Communities

  • Kazumasa Yamagishi,
  • Isao Muraki,
  • Yasuhiko Kubota,
  • Mina Hayama-Terada,
  • Hironori Imano,
  • Renzhe Cui,
  • Mitsumasa Umesawa,
  • Yuji Shimizu,
  • Tomoko Sankai,
  • Takeo Okada,
  • Shinichi Sato,
  • Akihiko Kitamura,
  • Masahiko Kiyama,
  • Hiroyasu Iso

DOI
https://doi.org/10.2188/jea.JE20180196
Journal volume & issue
Vol. 29, no. 3
pp. 83 – 91

Abstract

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The Circulatory Risk in Communities Study (CIRCS) is an ongoing community-based epidemiological study of lifestyle-related disease involving dynamic prospective cohorts of approximately 12,000 adults from five communities of Japan: Ikawa, Ishizawa and Kita-Utetsu (Akita Prefecture), Minami-Takayasu (Osaka Prefecture), Noichi (Kochi Prefecture), and Kyowa (Ibaraki Prefecture). One of the most notable features of CIRCS is that it is not only an observational cohort study to identify risk factors for cardiovascular diseases (CVD), such as stroke, coronary heart disease, and sudden cardiac death, but it also involves prevention programs for CVD. Using basic, clinical, epidemiological, and statistical techniques, CIRCS has clarified characteristics of CVD and the related risk factors to develop specific methodologies towards CVD prevention in Japanese middle-aged or older adults for more than half a century.

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