Nature Communications (Aug 2018)
Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia
- Julien Bryois,
- Melanie E. Garrett,
- Lingyun Song,
- Alexias Safi,
- Paola Giusti-Rodriguez,
- Graham D. Johnson,
- Annie W. Shieh,
- Alfonso Buil,
- John F. Fullard,
- Panos Roussos,
- Pamela Sklar,
- Schahram Akbarian,
- Vahram Haroutunian,
- Craig A. Stockmeier,
- Gregory A. Wray,
- Kevin P. White,
- Chunyu Liu,
- Timothy E. Reddy,
- Allison Ashley-Koch,
- Patrick F. Sullivan,
- Gregory E. Crawford
Affiliations
- Julien Bryois
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Melanie E. Garrett
- Duke Molecular Physiology Institute
- Lingyun Song
- Center for Genomic and Computational Biology, Duke University
- Alexias Safi
- Center for Genomic and Computational Biology, Duke University
- Paola Giusti-Rodriguez
- Department of Genetics, University of North Carolina
- Graham D. Johnson
- Center for Genomic and Computational Biology, Duke University
- Annie W. Shieh
- Department of Psychiatry, SUNY Upstate Medical University
- Alfonso Buil
- Research Institute of Biological Psychiatry, Mental Health Center Sct. Hans
- John F. Fullard
- Department of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai
- Panos Roussos
- Department of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai
- Pamela Sklar
- Department of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai
- Schahram Akbarian
- Department of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai
- Vahram Haroutunian
- Department of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai
- Craig A. Stockmeier
- Department of Psychiatry and Human Behavior, Center for Psychiatric Neuroscience, University of Mississippi Medical Center
- Gregory A. Wray
- Center for Genomic and Computational Biology, Duke University
- Kevin P. White
- Department of Human Genetics, University of Chicago
- Chunyu Liu
- Department of Psychiatry, SUNY Upstate Medical University
- Timothy E. Reddy
- Center for Genomic and Computational Biology, Duke University
- Allison Ashley-Koch
- Duke Molecular Physiology Institute
- Patrick F. Sullivan
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Gregory E. Crawford
- Center for Genomic and Computational Biology, Duke University
- DOI
- https://doi.org/10.1038/s41467-018-05379-y
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 15
Abstract
Chromatin accessibility may be altered in disease states. Here the authors carry out ATAC-seq on a large number of samples of dorsolateral prefrontal cortex from individuals with schizophrenia, and healthy controls.
