Takayasu’s disease effects on the kidneys: current perspectives

Abstract

Gioacchino Li Cavoli,1 Giuseppe Mulè,2 Mario Giuseppe Vallone,3 Flavia Caputo1 1Nephrology, Dialysis and Renal Transplant Department, Civico and Di Cristina Hospital, Palermo, Italy; 2Internal Medicine, Cardiovascular and Renal Diseases Department, University of Palermo, Palermo, Italy; 3Radiology Department, Civico and Di Cristina Hospital, Palermo, Italy Abstract: Takayasu arteritis (TA) is a chronic vasculitis disease of unknown etiology. Clinically significant renal disease is relatively common, and renovascular hypertension is the major renal problem. The assessment of TA activity is usually challenging because vascular inflammation may progress to fixed vascular injury without findings of active disease. Until now, the best therapeutic options have not been identified. This review highlights the current perspectives of renal involvement in TA. Keywords: arteritis, kidney involvement, large vessel vasculitis

Keywords

• Takayasu's disease
• Kidney involvement
• Large vessel vasculitis