Radiology Case Reports (Nov 2024)

Lipoleiomyosarcoma with pleomorphic liposarcoma of the uterus: Computed tomography findings with pathological correlation. A case report and review of literature

  • Valerio Arpaia, MD,
  • Luigi Pirolo, MD,
  • Stefania Sfregola, MD,
  • Luana Licata, MD,
  • Maria Iovino, MD,
  • Luca Sanduzzi, MD,
  • Anna Ferrante, MD,
  • Elisa Varriale, MD,
  • Pietro Iacobelli, MD,
  • Fabio Sandomenico, MD

Journal volume & issue
Vol. 19, no. 11
pp. 5474 – 5480

Abstract

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Uterine lipoleiomyosarcomas (L-LMS) are rare malignant tumors with only few cases descripted in literature. As well, liposarcomas (LPS) arising from uterine corpus are extremely rare since fat tissue is commonly poor or absent in uterus. We report a case of L-LMS of the uterine corpus with an associated component of pleomorphic LPS. As for other female pelvic malignancies, these neoplasms are more common in postmenopausal women and clinical findings are nonspecific. Most frequent signs and symptoms are metrorrhagia and abdominal pain often associated with pelvic distension/mass. We describe diagnostic and therapeutic steps of our patient from acceptation to conclusive diagnosis. In this case, contrast-enhanced computed tomography (CECT) depicted pivotal diagnostic findings and showed a clear distinction between different tumor components. Therefore, our goal with this essay is to stress the role of CECT imaging for diagnosis of these rare neoplasms. We also perform a review of current literature about liposarcomas of the uterine corpus.

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