In situ 3D bioprinting with bioconcrete bioink

Mingjun Xie; Yang Shi; Chun Zhang; Mingjie Ge; Jingbo Zhang; Zichen Chen; Jianzhong Fu; Zhijian Xie; Yong He

doi:10.1038/s41467-022-30997-y

Nature Communications (Jun 2022)

In situ 3D bioprinting with bioconcrete bioink

Mingjun Xie,
Yang Shi,
Chun Zhang,
Mingjie Ge,
Jingbo Zhang,
Zichen Chen,
Jianzhong Fu,
Zhijian Xie,
Yong He

Affiliations

Mingjun Xie: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Yang Shi: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Chun Zhang: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Mingjie Ge: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Jingbo Zhang: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Zichen Chen: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Jianzhong Fu: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University
Zhijian Xie: Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Yong He: State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Zhejiang University

DOI: https://doi.org/10.1038/s41467-022-30997-y
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 12

Abstract

Read online

Bioinks used in current in-situ bioprinting have limitations when applied to complex operational environments. Here, the authors report on the creation of a microgel reinforced GelMA bioink which can be simply prepared and used in different biomedical settings. The application is demonstrated in a cranial defect model.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal