Nature Communications (May 2021)

Learning a genome-wide score of human–mouse conservation at the functional genomics level

  • Soo Bin Kwon,
  • Jason Ernst

DOI
https://doi.org/10.1038/s41467-021-22653-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Understanding conserved functional genomic properties between human and mouse provides important context for mouse model studies. Here, the authors present a genome-wide conservation score integrating epigenomic, transcription factor binding, and transcriptomic data from mouse and human genomes.