Egyptian Journal of Medical Research (Jun 2021)

A pharmacovigilance Study on Critically Ill Patients Admitted In Beni-Suef University Teaching Hospital.

  • Alshimaa Mohamed Abdelmohymen,
  • Fatma Abdel Haleem Mahmoud,
  • Eman Hassan Nadwa,
  • Abdalaziz Mostafa Ahmed

DOI
https://doi.org/10.21608/ejmr.2021.175723
Journal volume & issue
Vol. 2, no. 2
pp. 170 – 202

Abstract

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The significance of adverse drug reactions (ADRs) among hospitalized patients particularly fundamentally sick patients conceded in the emergency unit has now turned into a worldwide concern. Albeit numerous clinical preliminaries have been directed on medication treatment in fundamentally sick patients, there are no adequate information on the wellbeing of the medication treatment utilized. The present work is a prospective observational study that was carried out in the ICU department, Benisuef teaching hospital, between August 2015 to December 2016, in which one hundred patients; admitted to the ICU, were enrolled. Patients who experienced drug related problems in the form of ADRs and/or adverse drug-drug interactions (DDIs) were recorded. The ADRs were analyzed regarding the incidence (88%), factors affecting the incidence, characteristics (most of ADRs were moderate, preventable, probable and type "A"). Clinically relevant adverse DDIs were analyzed regarding the incidence, mechanism, causal drugs and management plans.

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