Journal of Indian Academy of Oral Medicine and Radiology (Jan 2018)

A novel treatment modality for recurrent aphthous stomatitis – Single application of doxycycline hyclate

  • R Thriveni,
  • Gulnaaz Anjum,
  • D N S V Ramesh,
  • Amit Byatnal,
  • Mahalakshmi Wale,
  • K Pragati

DOI
https://doi.org/10.4103/jiaomr.jiaomr_135_17
Journal volume & issue
Vol. 30, no. 1
pp. 96 – 98

Abstract

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Background and Objectives: Recurrent aphthous ulcers are common painful mucosal conditions affecting the oral cavity. Despite of so many treatment modalities, there is no specific and definitive treatment. Hence a study was carried out to evaluate the clinical effects Single Application of Doxycycline Hyclate 100 mg for Recurrent apthous Stomatitis (RAS). Materials and Methods: Forty study subjects were included in the study. Patients were randomly assigned into two groups. There were 20 patients in each group; Group A patients received Doxycycline Hyclate 100 mg in the first visit, Group B patients received placebo. The results were analyzed with unpaired 't' test. Results: The data indicated a significant reduction in pain in group A (i.e., faster reduction in pain) compared with group B. Interpretation and Conclusion: A single application of doxycycline hyclate decreased pain and speeded recovery.

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