Nuclear fate of yeast snoRNA is determined by co-transcriptional Rnt1 cleavage

Pawel Grzechnik; Sylwia A. Szczepaniak; Somdutta Dhir; Anna Pastucha; Hannah Parslow; Zaneta Matuszek; Hannah E. Mischo; Joanna Kufel; Nicholas J. Proudfoot

doi:10.1038/s41467-018-04094-y

Nature Communications (May 2018)

Nuclear fate of yeast snoRNA is determined by co-transcriptional Rnt1 cleavage

Pawel Grzechnik,
Sylwia A. Szczepaniak,
Somdutta Dhir,
Anna Pastucha,
Hannah Parslow,
Zaneta Matuszek,
Hannah E. Mischo,
Joanna Kufel,
Nicholas J. Proudfoot

Affiliations

Pawel Grzechnik: Sir William Dunn School of Pathology, University of Oxford
Sylwia A. Szczepaniak: Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw
Somdutta Dhir: Sir William Dunn School of Pathology, University of Oxford
Anna Pastucha: Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw
Hannah Parslow: School of Biosciences, University of Birmingham
Zaneta Matuszek: Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw
Hannah E. Mischo: Sir William Dunn School of Pathology, University of Oxford
Joanna Kufel: Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw
Nicholas J. Proudfoot: Sir William Dunn School of Pathology, University of Oxford

DOI: https://doi.org/10.1038/s41467-018-04094-y
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 14

Abstract

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Small nucleolar ribonucleoprotein complexes (snoRNP) are fundamental for ribosome biogenesis. Here the authors provide insight into the 5ʹend processing of S. cerevisiae snoRNA and its important role in downstream nuclear events.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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